Peter van Galen
Peter van Galen
Brigham and Women's Hospital, Harvard Medical School, Broad Institute of MIT and Harvard
Verified email at - Homepage
Cited by
Cited by
Stem cell gene expression programs influence clinical outcome in human leukemia
K Eppert, K Takenaka, ER Lechman, L Waldron, B Nilsson, P Van Galen, ...
Nature medicine 17 (9), 1086-1093, 2011
Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer
A Kreso, CA O'Brien, P Van Galen, OI Gan, F Notta, AMK Brown, K Ng, ...
Science 339 (6119), 543-548, 2013
Single-cell RNA-seq reveals AML hierarchies relevant to disease progression and immunity
P van Galen, V Hovestadt, MH Wadsworth II, TK Hughes, GK Griffin, ...
Cell 176 (6), 1265-1281. e24, 2019
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ...
Science 360 (6386), 331-335, 2018
Self-renewal as a therapeutic target in human colorectal cancer
A Kreso, P Van Galen, NM Pedley, E Lima-Fernandes, C Frelin, T Davis, ...
Nature medicine 20 (1), 29-36, 2014
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance
BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ...
Cell Stem Cell 20 (2), 233-246. e7, 2017
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
P van Galen, A Kreso, N Mbong, DG Kent, T Fitzmaurice, JE Chambers, ...
Nature 510 (7504), 268-272, 2014
miR-126 regulates distinct self-renewal outcomes in normal and malignant hematopoietic stem cells
ER Lechman, B Gentner, SWK Ng, EM Schoof, P van Galen, JA Kennedy, ...
Cancer cell 29 (2), 214-228, 2016
Dual targeting of oncogenic activation and inflammatory signaling increases therapeutic efficacy in myeloproliferative neoplasms
M Kleppe, R Koche, L Zou, P van Galen, CE Hill, L Dong, S De Groote, ...
Cancer cell 33 (1), 29-43. e7, 2018
Attenuation of miR-126 activity expands HSC in vivo without exhaustion
ER Lechman, B Gentner, P van Galen, A Giustacchini, M Saini, ...
Cell stem cell 11 (6), 799-811, 2012
A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia
AGX Zeng, S Bansal, L Jin, A Mitchell, WC Chen, HA Abbas, ...
Nature medicine 28 (6), 1212-1223, 2022
A multiplexed system for quantitative comparisons of chromatin landscapes
P van Galen, AD Viny, O Ram, RJH Ryan, MJ Cotton, L Donohue, ...
Molecular cell 61 (1), 170-180, 2016
Association of clonal hematopoiesis with chronic obstructive pulmonary disease
PG Miller, D Qiao, J Rojas-Quintero, MC Honigberg, AS Sperling, ...
Blood, The Journal of the American Society of Hematology 139 (3), 357-368, 2022
Integrated stress response activity marks stem cells in normal hematopoiesis and leukemia
P van Galen, N Mbong, A Kreso, EM Schoof, E Wagenblast, SWK Ng, ...
Cell reports 25 (5), 1109-1117. e5, 2018
EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression
A Renneville, P Van Galen, MC Canver, M McConkey, JM Krill-Burger, ...
Blood, The Journal of the American Society of Hematology 126 (16), 1930-1939, 2015
Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion
P van Galen, A Kreso, E Wienholds, E Laurenti, K Eppert, ER Lechman, ...
Cell stem cell 14 (1), 94-106, 2014
Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations
TE Miller, CA Lareau, JA Verga, EAK DePasquale, V Liu, D Ssozi, ...
Nature biotechnology 40 (7), 1030-1034, 2022
Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance
CE Eyler, H Matsunaga, V Hovestadt, SJ Vantine, P van Galen, ...
Genome biology 21, 1-21, 2020
Chromatin accessibility promotes hematopoietic and leukemia stem cell activity
L Cabal-Hierro, P van Galen, MA Prado, KJ Higby, K Togami, CT Mowery, ...
Nature communications 11 (1), 1406, 2020
Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells
SJ Shareef, SM Bevill, AT Raman, MJ Aryee, P van Galen, V Hovestadt, ...
Nature biotechnology 39 (9), 1086-1094, 2021
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