| Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5263 | 2018 |
| Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins AM Verhagen, PG Ekert, M Pakusch, J Silke, LM Connolly, GE Reid, ... cell 102 (1), 43-53, 2000 | 3353 | 2000 |
| IAP antagonists target cIAP1 to induce TNFα-dependent apoptosis JE Vince, WWL Wong, N Khan, R Feltham, D Chau, AU Ahmed, ... Cell 131 (4), 682-693, 2007 | 1256 | 2007 |
| Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach L Zender, MS Spector, W Xue, P Flemming, C Cordon-Cardo, J Silke, ... Cell 125 (7), 1253-1267, 2006 | 1237 | 2006 |
| The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ... Immunity 39 (3), 443-453, 2013 | 1137 | 2013 |
| Linear ubiquitination prevents inflammation and regulates immune signalling B Gerlach, SM Cordier, AC Schmukle, CH Emmerich, E Rieser, TL Haas, ... Nature 471 (7340), 591-596, 2011 | 966 | 2011 |
| Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction TL Haas, CH Emmerich, B Gerlach, AC Schmukle, SM Cordier, E Rieser, ... Molecular cell 36 (5), 831-844, 2009 | 853 | 2009 |
| HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins AM Verhagen, J Silke, PG Ekert, M Pakusch, H Kaufmann, LM Connolly, ... Journal of Biological Chemistry 277 (1), 445-454, 2002 | 794 | 2002 |
| IAPs, RINGs and ubiquitylation DL Vaux, J Silke Nature reviews Molecular cell biology 6 (4), 287-297, 2005 | 791 | 2005 |
| Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome VS Marsden, L O'Connor, LA O'Reilly, J Silke, D Metcalf, PG Ekert, ... Nature 419 (6907), 634-637, 2002 | 719 | 2002 |
| Caspase inhibitors PG Ekert, J Silke, DL Vaux Cell Death & Differentiation 6 (11), 1081-1086, 1999 | 652 | 1999 |
| RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL KE Lawlor, N Khan, A Mildenhall, M Gerlic, BA Croker, AA D’Cruz, C Hall, ... Nature communications 6 (1), 6282, 2015 | 595 | 2015 |
| RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ... Cell 157 (5), 1175-1188, 2014 | 587 | 2014 |
| XIAP discriminates between type I and type II FAS-induced apoptosis PJ Jost, S Grabow, D Gray, MD McKenzie, U Nachbur, DCS Huang, ... Nature 460 (7258), 1035-1039, 2009 | 578 | 2009 |
| Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ... Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014 | 554 | 2014 |
| Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation JE Vince, WWL Wong, I Gentle, KE Lawlor, R Allam, L O'Reilly, K Mason, ... Immunity 36 (2), 215-227, 2012 | 521 | 2012 |
| AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC V Sagulenko, SJ Thygesen, DP Sester, A Idris, JA Cridland, PR Vajjhala, ... Cell Death & Differentiation 20 (9), 1149-1160, 2013 | 491 | 2013 |
| The diverse role of RIP kinases in necroptosis and inflammation J Silke, JA Rickard, M Gerlic Nature immunology 16 (7), 689-697, 2015 | 487 | 2015 |
| The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity RB Damgaard, U Nachbur, M Yabal, WWL Wong, BK Fiil, M Kastirr, ... Molecular cell 46 (6), 746-758, 2012 | 403 | 2012 |
| The Drosophila caspase DRONC is regulated by DIAP1 P Meier, J Silke, SJ Leevers, GI Evan The EMBO journal, 2000 | 383 | 2000 |
Najoua LalaouiGroup Leader, Peter MacCallum Cancer CenterBestätigte E-Mail-Adresse bei petermac.org
