Mark A. Kay
Mark A. Kay
Verified email at
Cited by
Cited by
Progress and problems with the use of viral vectors for gene therapy
CE Thomas, A Ehrhardt, MA Kay
Nature Reviews Genetics 4 (5), 346-358, 2003
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
CS Manno, GF Pierce, VR Arruda, B Glader, M Ragni, JJE Rasko, ...
Nature medicine 12 (3), 342-347, 2006
Adenovirus-associated virus vector–mediated gene transfer in hemophilia B
AC Nathwani, EGD Tuddenham, S Rangarajan, C Rosales, J McIntosh, ...
New England Journal of Medicine 365 (25), 2357-2365, 2011
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
D Grimm, KL Streetz, CL Jopling, TA Storm, K Pandey, CR Davis, ...
Nature 441 (7092), 537-541, 2006
Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics
MA Kay, JC Glorioso, L Naldini
Nature medicine 7 (1), 33-40, 2001
RNA interference in adult mice
AP McCaffrey, L Meuse, TTT Pham, DS Conklin, GJ Hannon, MA Kay
Nature 418 (6893), 38-39, 2002
Long-term safety and efficacy of factor IX gene therapy in hemophilia B
AC Nathwani, UM Reiss, EGD Tuddenham, C Rosales, P Chowdary, ...
New England Journal of Medicine 371 (21), 1994-2004, 2014
Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector
MA Kay, CS Manno, MV Ragni, PJ Larson, LB Couto, A McClelland, ...
Nature genetics 24 (3), 257-261, 2000
Inhibition of hepatitis B virus in mice by RNA interference
AP McCaffrey, H Nakai, K Pandey, Z Huang, FH Salazar, H Xu, ...
Nature biotechnology 21 (6), 639-644, 2003
A nonviral minicircle vector for deriving human iPS cells
F Jia, KD Wilson, N Sun, DM Gupta, M Huang, Z Li, NJ Panetta, ZY Chen, ...
Nature methods 7 (3), 197-199, 2010
AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B
CS Manno, AJ Chew, S Hutchison, PJ Larson, RW Herzog, VR Arruda, ...
Blood, The Journal of the American Society of Hematology 101 (8), 2963-2972, 2003
Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice
H Azuma, N Paulk, A Ranade, C Dorrell, M Al-Dhalimy, E Ellis, S Strom, ...
Nature biotechnology 25 (8), 903-910, 2007
State-of-the-art gene-based therapies: the road ahead
MA Kay
Nature Reviews Genetics 12 (5), 316-328, 2011
Sarcoma derived from cultured mesenchymal stem cells
J Tolar, AJ Nauta, MJ Osborn, A Panoskaltsis Mortari, RT McElmurry, ...
Stem cells 25 (2), 371-379, 2007
In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses
D Grimm, JS Lee, L Wang, T Desai, B Akache, TA Storm, MA Kay
Journal of virology 82 (12), 5887-5911, 2008
In vivo activity of nuclease-resistant siRNAs
JM Layzer, AP McCaffrey, AK Tanner, ZAN Huang, MA Kay, BA Sullenger
Rna 10 (5), 766-771, 2004
Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors
RO Snyder, CH Miao, GA Patijn, SK Spratt, O Danos, D Nagy, AM Gown, ...
Nature genetics 16 (3), 270-276, 1997
Human tRNA-derived small RNAs in the global regulation of RNA silencing
D Haussecker, Y Huang, A Lau, P Parameswaran, AZ Fire, MA Kay
Rna 16 (4), 673-695, 2010
Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8
K Inagaki, S Fuess, TA Storm, GA Gibson, CF Mctiernan, MA Kay, H Nakai
Molecular Therapy 14 (1), 45-53, 2006
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system
SR Yant, L Meuse, W Chiu, Z Ivics, Z Izsvak, MA Kay
Nature genetics 25 (1), 35-41, 2000
The system can't perform the operation now. Try again later.
Articles 1–20