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Miguel R. Lugo
Miguel R. Lugo
Research Associate, Univ. of Guelph
Verified email at uoguelph.ca
Title
Cited by
Cited by
Year
Interaction of LDS-751 with P-glycoprotein and mapping of the location of the R drug binding site
MR Lugo, FJ Sharom
Biochemistry 44 (2), 643-655, 2005
1502005
Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs
MR Lugo, FJ Sharom
Biochemistry 44 (42), 14020-14029, 2005
1212005
New insights into the drug binding, transport and lipid flippase activities of the p-glycoprotein multidrug transporter
FJ Sharom, MR Lugo, PDW Eckford
Journal of bioenergetics and biomembranes 37, 481-487, 2005
662005
C3larvin toxin, an ADP-ribosyltransferase from Paenibacillus larvae
D Krska, R Ravulapalli, RJ Fieldhouse, MR Lugo, AR Merrill
Journal of Biological Chemistry 290 (3), 1639-1653, 2015
602015
Scabin, a novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies
B Lyons, R Ravulapalli, J Lanoue, MR Lugo, D Dutta, S Carlin, AR Merrill
Journal of Biological Chemistry 291 (21), 11198-11215, 2016
582016
Time-resolved fluorescence resonance energy transfer shows that the bacterial multidrug ABC half-transporter BmrA functions as a homodimer
O Dalmas, MA Do Cao, MR Lugo, FJ Sharom, A Di Pietro, JM Jault
Biochemistry 44 (11), 4312-4321, 2005
402005
Diacylglycerol regulates the plasma membrane calcium pump from human erythrocytes by direct interaction
MC Pérez-Gordones, MR Lugo, M Winkler, V Cervino, G Benaim
Archives of biochemistry and biophysics 489 (1-2), 55-61, 2009
372009
Molecular dynamics and in silico mutagenesis on the reversible inhibitor-bound SARS-CoV-2 main protease complexes reveal the role of lateral pocket in enhancing the ligand affinity
YL Weng, SR Naik, N Dingelstad, MR Lugo, S Kalyaanamoorthy, ...
Scientific Reports 11 (1), 7429, 2021
362021
Characterization of the toxin Plx2A, a RhoA‐targeting ADP‐ribosyltransferase produced by the honey bee pathogen Paenibacillus larvae
J Ebeling, A Fünfhaus, H Knispel, D Krska, R Ravulapalli, KA Heney, ...
Environmental microbiology 19 (12), 5100-5116, 2017
292017
The father, son and cholix toxin: the third member of the DT group mono-ADP-ribosyltransferase toxin family
MR Lugo, AR Merrill
Toxins 7 (8), 2757-2772, 2015
272015
The 1.8 Å cholix toxin crystal structure in complex with NAD+ and evidence for a new kinetic model
RJ Fieldhouse, R Jørgensen, MR Lugo, AR Merrill
Journal of Biological Chemistry 287 (25), 21176-21188, 2012
262012
Characterization of Vis Toxin, a Novel ADP-Ribosyltransferase from Vibrio splendidus
R Ravulapalli, MR Lugo, R Pfoh, D Visschedyk, A Poole, RJ Fieldhouse, ...
Biochemistry 54 (38), 5920-5936, 2015
232015
Characterization of the catalytic signature of Scabin toxin, a DNA-targeting ADP-ribosyltransferase
B Lyons, MR Lugo, S Carlin, T Lidster, AR Merrill
Biochemical Journal 475 (1), 225-245, 2018
172018
Dynamics of Scabin toxin. A proposal for the binding mode of the DNA substrate
MR Lugo, B Lyons, C Lento, DJ Wilson, AR Merrill
PLoS One 13 (3), e0194425, 2018
152018
Membrane topology of the colicin E1 channel using genetically encoded fluorescence
D Ho, MR Lugo, AL Lomize, ID Pogozheva, SP Singh, AL Schwan, ...
Biochemistry 50 (22), 4830-4842, 2011
152011
Characterization of C3larvinA, a novel RhoA-targeting ADP-ribosyltransferase toxin produced by the honey bee pathogen, Paenibacillus larvae
M Turner, O Tremblay, KA Heney, MR Lugo, J Ebeling, E Genersch, ...
Bioscience reports 40 (1), BSR20193405, 2020
142020
A comparative structure‐function analysis of active‐site inhibitors of Vibrio cholerae cholix toxin
MR Lugo, AR Merrill
Journal of Molecular Recognition 28 (9), 539-552, 2015
142015
Structural variability of C3larvin toxin. Intrinsic dynamics of the α/β fold of the C3-like group of mono-ADP-ribosyltransferase toxins
MR Lugo, R Ravulapalli, D Dutta, AR Merrill
Journal of Biomolecular Structure and Dynamics 34 (12), 2537-2560, 2016
132016
Harmonic analysis of the fluorescence response of bimane adducts of colicin E1 at helices 6, 7, and 10
D Ho, MR Lugo, AR Merrill
Journal of Biological Chemistry 288 (7), 5136-5148, 2013
132013
Interaction of LDS-751 with the drug-binding site of P-glycoprotein: a Trp fluorescence steady-state and lifetime study
MR Lugo, FJ Sharom
Archives of biochemistry and biophysics 492 (1-2), 17-28, 2009
132009
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